Around 48 B.C. Cleopatra lost her royal authority to her brother. Deprived of royal privilages she withdrew into Syria and made preparations to recover her rights by force of arms. When Julius Caesar followed Pompey into Egypt she induced Caesar to undertake a war on her behalf.
In Rome, Cleopatra lived openly with Caesar as his mistress and was restored to her throne. When Caesar had his life taken from him in 44 B.C., aware of her unpopularity, she returned to Egypt. It is believed Caesar's only known son, Caesarion, was produced through his liaison with the queen.
Mark Antony (a Roman politician and genera), after the assassination of Caesar, helped form what is called Rome's Second Triumvirate with Octavian and Marcus Lepidus. This three-man dictatorship soon defeated, at the battle of Philippi in 42 B.C., those who had Caesar murdered. The three men divided the responsibilities of rule amongst themselves, with Antony assigned the empire's eastern provinces which included the client state of Egypt which Cleopatra had ruled.
Cleopatra soon became Antony's mistress and the couple eventually had three children. The Triumvirate broke apart in 33 B.C. Rome's Senate declared Antony a traitor and proclaimed a war against the Queen. In 31 B.C. Antony and Egypt's combined forces were defeated by Octavian at the battle of Actium. The couple soon fled to Egypt where Antony committed suicide.
Unable to ingratiate herself with Octavian (who assumed the title Augustus and became Rome's first emperor), Cleopatra committed suicide in August of 30 B.C. The Roman empire, which Egypt succumbed to, became the backdrop against which the Savior of the world, Jesus Christ, would be born as a flesh and blood human in the fall of 5 B.C. It was a Roman appointed King named Herod the Great who ordered the death of all children two years old or younger in an attempt to kill baby Jesus.