The most well-known Roman Prefect in history is Pontius Pilate. The Jewish religious leaders who hated Jesus brought him to Pilate because, as Rome's governing authority in the area, he alone had the power to execute criminals. The New Testament also mentions the interaction of two other Roman rulers of Judea with the most important person in the New Testament after Jesus himself - the apostle Paul.
In the late spring of 58 A.D. a riot at Jerusalem's temple ultimately leads to the apostle Paul's arrest by the Romans. Transported by armed guard out of Jerusalem, Paul is taken to Caesarea so that the accusations against him can be heard before Procurator Marcus Antonius Felix. The apostle is allowed to defend himself after Felix hears the testimony of several religious leaders who hate him and what he teaches. Felix, after hearing the apostle's defense, keeps him as a prisoner for at least two years in the hopes he will be BRIBED to free him! No bribe comes, however, and the case is left to Procurator Porcius Festus (Acts 24:22-27).
Not wanting to be transferred to Jerusalem for his trial, Paul exercises his right as a Roman citizen to have his case heard in Rome by Caesar himself! (Acts 25:1-2, 9-12).