Thanksgiving toward God for his many blessings and perfect love manifested on us is a common theme in the Bible. For example, ancient Israel annually observed seven periods, known as the Feast (Holy) days, which centered on the three main harvests. One of the central themes of these days is an acknowledgment that the Eternal makes possible our lives and that he is the source of our prosperity and wealth.
The actual word or its plural is found thirty times in the KJV, nine of which occur in the New Testament (2Corinthians 4:15, 9:11 - 12, Philippians 4:6, Colossians 2:7, 4:2, 1Timothy 4:3 - 4, Revelation 7:12). Of these nine occurrences, the apostle Paul refers to thanksgiving toward God eight times while John refers to it only once.
The Old Testament use of the word thanksgiving (in the majority of cases) comes from the Hebrew todah (Strong's Concordance #H8426), which means the extension of the hand. Brown-Driver-Briggs' Hebrew Definitions states this original language word means confession, praise or thanks made toward God which can take the form of offering praises, singing hymns and other songs, and so on.
An excellent example of praising the Eternal for his manifold blessings is found in the book of Revelation. It occurs after all those who are martyred in the Great Tribulation period are resurrected from the dead and made to stand before God's throne (Revelation 7:9, 13 - 14).
After these righteous people shout, "The salvation of our God has come" (verse 10, HBFV), all others in heaven (e.g. righteous angels, twenty-four spiritual elders, etc.) bow before the Almighty and say, "Blessing, and glory, and wisdom, and thanksgiving, and honor, and power and strength be to our God into the ages of eternity . . ." (verse 12, HBFV).
The Bible study site is sometimes asked what would be a good prayer to offer before partaking of a meal or on a special holiday like Thanksgiving. These, like most other kinds of prayers, should always be given from the heart. They should not be merely reciting something that is well known and memorized like the Lord's Prayer.
One suggested prayer of thanksgiving would be to first acknowledging God as our righteous and loving Father. Next, it would be appropriate to thank him for graciously allowing us to have a relationship with him and for bringing safely together those in attendance. This could be followed by thanking him for all our blessings, including the meal that will be eaten.
Any thanksgiving prayer should be closed in Jesus' name (John 16:23 - 24, 26). Examples in the Bible, for further study of thanking God, can be found in Exodus 15, Psalms 100, 103, 106 and 107, Luke 1:46 - 55, 2:13 - 14, Romans 11:33 - 36, and Revelation 5:8 - 14.
Thanksgiving to our great Father should be offered every time we pray (Ephesians 5:20, Philippians 4:6, 1Thessalonians 5:18). We should always acknowledge our physical, as well as spiritual, blessings we receive from his hand (Colossians 1:12, 1Timothy 4:3 - 4). Thanking God for his loving care and generosity towards us is the central meaning of the holiday.