The Meaning of Numbers: The Number 42
Forty-two is a number connected with Antichrist. An important part of his career is to last for 42 months (Revelation 11:2, 13:5), and thus 42 is fixed upon him:
1. Then the angel gave me a measuring rod like a staff, saying, "Arise and measure the temple of God, and the altar, and those who worship in it. 2. But leave out the court that is within the temple area, and do not measure it because it has been given up to the Gentiles; and they shall trample upon the holy city for forty-two months.
4. And they worshiped the dragon, who gave his authority to the beast. And they worshiped the beast, saying, "Who is like the beast? Who has the power to make war against him?" 5. And a mouth speaking great things and blasphemies was given to him; and authority was given to him to continue for forty-two months. (Revelation 11:1-2, 13:4-5, Holy Bible in Its Original Order - A Faithful Version (HBFV))
The factors of 42 are six and seven (6 x 7 = 42), and this shows a connection between man and the Spirit of God, and between Christ and Antichrist. Additionally, forty-two stages of Israel's wanderings mark their conflict with the will of God.
Being a multiple of seven, it might be supposed that it would be connected with spiritual perfection. But it is the product of six times seven. Six, therefore, representing Man, and man's opposition to God, Forty-two becomes significant of the working out of man's opposition to God.
There may be something more in the common phrase about things being all "sixes and sevens." They are so, indeed, when man is mixed up with the things of God, and when religious "flesh" engages in spiritual things.